PDO Filler
Rejubella
PDO dermal filler
01
PDO Microsphere
02
Safe & Quick Treatment
03
Natural Collagen Generation
04
Enhancement of Facial Health
A polymer filler made by a new form of PDO whose stability has been confirmed for over 40 years.
PDO dermal filler Rejubella aims to promote collagen production and maintain volume.
Rejubella improves the fundamental deficiency of volume by collagen restoration.
Specification
Patent 10-2019-0124485
Product of uniform size Microsphere PDO particles
PDO Microsphere Features
The surface is smooth spherical and even particle
Cannula size : 26G
Size : 10-60μm
Capacity : 300mg/vial,
1vial/box or 5vial/box
PDO(polydioxanone) 150mg
+
CMC 150mg
Surface area of one PDO microsphere : 0.00608mm2
Surface area of approximately 2.6 million PDO microspheres of Rejubella : 15,800mm2
Surface area of one PDO mono thread (USP6-0 50mm) : 11.0mm2
Similar effect to 1,436 PDO mono threads
1Week
4Weeks
Collagen Generation
PDO fillers stimulate the skin through normal metabolic processes in the body.
As the fibroblasts of the irritated skin are active, it promotes regeneration of collagen and various skin tissues, improving the volume and elasticity.
Function Comparison
| # | METABIOMED | company A | company B |
|---|---|---|---|
| Image |  |
 |
 |
| Main ingredient | PDO (Polydioxanone) | PCL (Polycaprolactone) | PLLA (Poly-L-Lactic acid) |
| Component |
PDO150mg + CMC150mg |
PCL30% + CMC70% |
PLLA150mg + CMC90mg + Mannitol127.5mg |
| Total capacity | 300mg / 5ml* | 1cc | 367.5mg / 5ml* |
| Decomposition period | 1 year | 1~4 years | 2~2.5 years |
| Particle size | 10-60μm | 25-50μm | 40-63μm |
| Particle shape | Uniform spherical | Uniform spherical | Sharp non-uniform |
| Type | Powder | Liquid | Powder |
Rejubella is a filler that consists of stable PDO microspheres developed by Metabiomed, and has fewer side effects and shorter preparation time compared to other companies.
Mechanism Process
1
Before Treatment
2
Making Volume
3
Back to Original State
4
Collagen Generation Increase of Dermal Thickness
How to use
1
Inject 5ml of sterile water into 1vial by a syringe with a sterile 18g needle.(add 1~2ml of lidocaine)
2
Shake enough to completely hydrate the product.
3
After shaking the vial to make a suspension, take an appropriate amount of the product with 1-3ml sterile syringe and a new 18g needle.
4
Use the product after connecting 26g needle to the syringe.
Safe & Biodegradable
0 day
1 week
1 month
2 month
3 month
5 month
6 month
METABIOMED
company A
company B
Ref) Osong Advanced Medical Innovation Foundation Laboratory Animal Center
Changes of filler volume
In the case of the product of companyA and companyB, it was confirmed that all substances in the body were biodegraded at the first month. And in the case of Rejubella, all substances in the body were biodegraded at the 5th month.
As Rejubella slowly biodegrades, the effect of self-generation lasts for a long time.
Self healing process stimulates collagen and elastin production during hydrolysis.
PDO powder filler Areas
Wrinkle improvement
- 1Frown Lines
- 2Brow(worry) Lines
- 3Eye Brow
- 4Crow’s Feet
- 5Nosolabial folds
- 6Marionette Lines
Volume
- 7Cheek Augmentation
- 8Fill temple depressions
- 9Chin Augmentation
Scaffold
- 10Nose
Whitening
Rejuvenation