Skin Booster
K Booster
NO.1 SKIN BOOSTER IN KOREA.
A NEW STANDARD SKIN BOOSTER FOR SKIN REJUVENATION.
IDEAL ECM SKINBOOSTER FOR DERMAL BIOGENESIS.
OPTIMAL BIOSTIMULATING FORMULAR FOR DERMAL FIBROBLAST.
When a flower doesn't bloom, you fix the environment in which it grows, not the flower
ㆍ Alexander Den Heijer ㆍ
K-Booster Can Improving of Dermal ECM Environment (Ha+54 Essential Ingredient)
Healthy Skin
Aging Skin
Effects of Photodamage and Aging
k-Booster is Optimal Biostimulating formular for Dermal Fibroblast (Growth Factor)
FIBROBLAST ROLE
Fibroblast is a Key Maintainer of ECM Networks
FIBROBLAST
Fibroblast Stimulation → Collagen, Elatin Formation
K Booster indication
- +for men and women of all skin type
- +for people with younger or more mature skin
- +for the face, neck, hands & decolletage
- +for people improve acne scarred or photodamaged skin
01 K-Booster A AQUA
INCLUDE 4 kinds of Growth factors
+Hyaluronic acid (0.3%)
+12 Vitamines
24 Amino acids
6 Co-enzymes
6 Minerals
5 Nucleic acid
1 Anti-oxidant
+EGF | IGF-1 | bFGF | AQP
INDICATION
- Skin Hydration
- Improve Radiance
- Skin Revitalization
- Biostimulation of Dermal Fibroblast
02 K-Booster W WHITENING
INCLUDE 2 kinds of Plant callus extracts
+Hyaluronic acid (0.5%)
+12 Vitamines
24 Amino acids
6 Co-enzymes
6 Minerals
5 Nucleic acid
1 Anti-oxidant
+Citrus Junos Callus Extract
Pyrus Serotina Callus Extract
INDICATION
- Hydration
- Radiance
- Improve Skin Tone
- Reduce Melasma
03 K-Booster R REJUVENATION
INCLUDE 20 kinds of Growth factors
+Hyaluronic acid (0.5%)
+12 Vitamines
24 Amino acids
6 Co-enzymes
6 Minerals
5 Nucleic acid
1 Anti-oxidant
+EGF | IGF-1 | bFGF | AQP | aFGF | VEGFA | PDGFA | PDGFB | PGF | SCF | COL3A1 | KGF | hGH | HSP70 | SIRT1 | SIRT2 | SOD | TRX | TGF-b1 | TGF-b3
INDICATION
- More Powerful Hydration
- Rediance & Revitalization
- Biostimulation of Fibroblast
- Remove Fine Line
- Scar Treatment
04 K-Booster PDRN PLUS
INCLUDE 20 kinds of Plant callus extracts
+Hyaluronic acid (0.5%)
+12 Vitamines
24 Amino acids
6 Co-enzymes
6 Minerals
5 Nucleic acid
1 Anti-oxidant
+EGF | IGF-1 | bFGF | AQP | aFGF | VEGFA | PDGFA | PDGFB | PGF | SCF | COL3A1 | KGF | hGH | HSP70 | SIRT1 | SIRT2 | SOD | TRX | TGF-b1 | TGF-b3
+ PDRN
INDICATION
- Massice Hydration
- Rediance & Revitalization
- Biostimulation of Fibroblast
- Boost cell renewal
- Collagen genetarion
- Minimize Pores
- Remove Wrinkles and Scars
- Increase Skin Volume
Development Background
We want to develop an optimal solution to improve the ECM environment of the dermis and to promote the growth of human keratinocytes to suppress aging.
01 K-complex optimal combination The optimal booster combination was found through cell testing of various combinations of booster.
Fig 1. The effect of K-Complex on human keratinocytes
The cytotoxicity and cell proliferation of human keratinocytes were tested by MIT assay. As a result, it was confirmed that the combination of No. 8 test group showed about 180% cell proliferation ability compared with the control group.
02 Comparative test As a result of comparing with the product of A company, K-complex was not cytotoxic even in 50% treatment group.
A
B
Fig 2. Comparison of K-Complex with product A
A comparative test of the basic base composition of product A (A) and K-Complex (B) was tested in human keratinocytes. As a result, it was confirmed that K-Complex does not show cytotoxicity even at a higher concentration than the product A.
03 Optimization of K-Booster 1 For maximize cell proliferation, K-complex combined with optimal combination of growth factors. It was branded as K-Booster.
Fig 3. Effect of K-Booster on human keratinocytes (1)
In order to enhance the efficacy of the K-Complex, the growth factor was tested in human keratinocytes by adding growth factors at an optimal ratio. As a result, it was confirmed that the cell proliferation effect was significantly enhanced when treated with the growth factor, rather than adding K-Complex alone.
04 Optimization of K-Booster II It improves product quality through sterilization process and is safer to skin.
Fig 4. Effect of K-Booster on human keratinocytes (2)
In order to commercialize K-Booster, 1,2-hexanediol was prescribed to confirm efficacy in the final product. As a result, it was confirmed that cell proliferation is promoted even in the final product.
Cell Test
05 Promotes skin cell proliferation and activity
The K-booster solution was treated up to 50% in human keratinocytes, Cell proliferation increased by about 40% compared to the control group.
A. Human keratinocyte proliferation test
Control
K-Booster treated
B. Human fibroblast proliferation test
Control
K-Booster treated
Fig 5. Effect of K-Booster on human skin cells
The proliferative potential of K-Booster in human skin cells was visually observed. As a result, the cell proliferation was significantly promoted in the K-Booster test group.
06 Promotes skin cell proliferation and activity
Promoting skin cell wound regeneration : K-Booster promotes wound regeneration in a concentration-dependent manner.
Control
K-Booster 6.25% treated
K-Booster 25% treated
Fig 6. Effect of K-Booster on wound regeneration in human keratinocytes
The wound regeneration effect of K-Booster in human keratinocytes was examined. As a result, it was confirmed that the woundregeneration rate was remarkably faster in the K-Booster 25% test group as compared with the control group.
Wrinkles in the eyes (at 2 weeks interval • 5 times)
Wrinkles in the eyes (at 2 weeks interval. 5 times)
Acne & trouble skin (at 2 weeks interval. 5 times)
Pigmentation (at 2 weeks interval. 5 times)
Flush & pore (at 2 weeks interval · 5 times)
Freckle (at 2 weeks interval • 5 times)
Freckle (at 2 weeks interval • 5 times)
Wrinkles in back of hand (at 2 weeks interval. 5 times)
