BoneMedik-S

Coralline Hydroxyapatite Bone Graft Substitute

Advantages

No Biological Rejection
No Disease Transmission
No Additional Surgery Necessary to Collect the Bone for Grafting
Offer an Interconnected Porosity Similar to Human Cancellous Bone

Provide a Framework Which the Host Bone can Regenerate & Heal
USA- Patented Silicon Ion Containing HA Speeds Up the Bone Regeneration (Si-Content : Avg. 0.6wt%)
Under Strict FDA Regulations & GMP Compliance, Ensuring the Highest Product Quality

AP(Alkaline Phosphate) Activity

This figure shows alkaline phosphate (AP) activity in human mesenchymal stem cells cultured on BD and BoneMedik-S.

AP is an enzyme whose activity refl ects diff erentiation of human mesenchymal stem cells to bone forming osteoblastic cells.

Higher AP activity means the human mesenchymal stem cells are diff erentiating towards the bone forming osteoblast phenotype to a greater degree.

Cells were cultured on calcium phosphate scaff old, Catalog No. 354617 (BD), BoneMedik-S scaff old (Coral).

The fact that AP is higher in human mesenchymal stem cells on BoneMedik-S (coral) than in human mesenchymal cells on BD suggest that cell on BoneMedik-S are better able to form bone than cells on BD.

These preclinical data suggest BoneMedik-S might be superior to other scaff olds in stimulating bone growth.

(Pre-Study in Penn State Hershey Milton. S. Medical Center in PA, USA / META R&D Institute, KOREA. 2009)